4.1 Application of this guide will provide users with information on how to use the various documents listed in Section 2 related to health and safety of metalworking and metal removal fluids.
4.2 Users of the documents listed in Section 2 may fall into several categories, such as producers of metalworking or metal removal fluids, suppliers of raw materials to those producers, users of metalworking or metal removal fluids, and other interested parties, such as non governmental organizations.
4.3 While all parties may wish to be generally familiar with all the documents listed in Section 2, producers and users may each want to focus on certain documents which are directly applicable to them:
4.4 Documents Applicable to Producers:
4.4.1 E1687 Test Method for Determining Carcinogenic Potential of Virgin Base Oils in Metalworking Fluids
4.4.1.1 Test Method E1687 covers a microbiological test procedure based upon the Salmonella mutagenesis assay of Ames et. al6 (see also Maron et al7). It can be used as a screening technique to detect the presence of potential dermal carcinogens in virgin base oils used in the formulation of metalworking oils. Persons who use this test should be well-versed in the conduct of the Ames test and conversant with the physical and chemical properties of petroleum products.
4.4.1.2 Producers of metalworking fluids and metal removal fluids should assure themselves that virgin base oils used in the formulation of neat metalworking and metal removal oils and soluble and semi-synthetic metal removal fluids have an acceptable mutagenicity index or mutagenic potency index.
4.4.2 E1302 Guide for Acute Animal Toxicity Testing of Water-Miscible Metal Removal Fluids
4.4.2.1 Guide E1302 defines acute animal toxicity tests and sets forth references for procedures to assess the acute toxicity of water-miscible metal removal fluids as manufactured.
4.4.2.2 Application of Guide E1302 will provide information on the acute toxicity of water-miscible metal removal fluids and will assist the user in evaluating the potential health hazards of the fluid and developing appropriate work practices.
4.5 Documents Applicable to Users:......ASTM E2148-16 history
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