ISO 23970:2021
Milk, milk products and infant formula - Determination of melamine and cyanuric acid by liquid chromatography and tandem mass spectrometry (LC-MS/MS)

Standard No.
ISO 23970:2021
Release Date
2021
Published By
International Organization for Standardization (ISO)
Latest
ISO 23970:2021
Scope
This document specifies a method for the determination of melamine and cyanuric acid with liquid chromatography in combination with tandem mass spectrometry (LC-MS/MS). The method has been validated in an interlaboratory study via the analysis of spiked samples of milk-based infant formula, soy-based infant formula, milk powder, whole milk, soy drink and milk chocolate ranging from 0,71 mg/kg to 1,43 mg/kg for melamine and 0,57 mg/kg to 1,45 mg/kg for cyanuric acid. The limits of quantification (LOQ) for melamine and cyanuric acid in food are 0,05 mg/kg and 0,25 mg/kg, respectively. The upper limit of the working range is up to 10 mg/kg for melamine and up to 25 mg/kg for cyanuric acid.

ISO 23970:2021 Referenced Document

  • ISO 3696 Water for analytical laboratory use; Specification and test methods

ISO 23970:2021 history

  • 2021 ISO 23970:2021 Milk, milk products and infant formula - Determination of melamine and cyanuric acid by liquid chromatography and tandem mass spectrometry (LC-MS/MS)
Milk, milk products and infant formula - Determination of melamine and cyanuric acid by liquid chromatography and tandem mass spectrometry (LC-MS/MS)



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