DS/EN ISO 21427-2:2009
Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2: Mixed population method using the cell line V79

Standard No.

DS/EN ISO 21427-2:2009

Release Date

2009

Published By

Danish Standards Foundation

Status

Be replaced 2009-07

Replace By

DS/EN ISO 21427-2/AC:2009

Latest

DS/EN ISO 21427-2/AC:2009

Replace

DS/ISO 21427-2:2007

Scope

This part of ISO 21427-2 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes.The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.

DS/EN ISO 21427-2:2009 history

• 2009 DS/EN ISO 21427-2/AC:2009 Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2: Mixed population method using the cell line V79
• 2009 DS/EN ISO 21427-2:2009 Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2: Mixed population method using the cell line V79
• 0000 DS/ISO 21427-2:2007