ASTM E2834-12
Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA)

Standard No.

ASTM E2834-12

Release Date

2012

Published By

American Society for Testing and Materials (ASTM)

Status

Be replaced

Replace By

ASTM E2834-12(2018)

Latest

ASTM E2834-12(2022)

Scope

NTA is one of the very few techniques that are able to deal with the measurement of particle size distribution in the nano-size region. This Guide describes the NTA technique for direct visualization and measurement of Brownian motion, generally applicable in the particle size range from several nanometers until the onset of sedimentation in the sample. The NTA technique is usually applied to dilute suspensions of solid material in a liquid carrier. It is a first principles method (that is, calibration in the standard understanding of this word, is not involved). The measurement is hydrodynamically based and therefore provides size information in the suspending medium (typically water). Thus the hydrodynamic diameter will almost certainly differ from size diameters determined by other techniques and users of the NTA technique need to be aware of the distinction of the various descriptors of particle diameter before making comparisons between techniques (see 8.7). Notwithstanding the preceding sentence, the technique is routinely applied in industry and academia as both a research and development tool and as a QC method for the characterization of submicron systems.

1.1 This guide deals with the measurement of particle size distribution of suspended particles, from ~10 nm to the onset of sedimentation, sample dependent, using the nanoparticle tracking analysis (NTA) technique. It does not provide a complete measurement methodology for any specific nanomaterial, but provides a general overview and guide as to the methodology that should be followed for good practice, along with potential pitfalls.

1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

ASTM E2834-12 Referenced Document

• ASTM C322 Standard Practice for Sampling Ceramic Whiteware Clays
• ASTM E1617 Standard Practice for Reporting Particle Size Characterization Data
• ASTM E2490 Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Photon Correlation Spectroscopy (PCS)
• ASTM E456 Standard Terminology for Relating to Quality and Statistics
• ISO 13320 Particle size analysis — Laser diffraction methods
• ISO 13321 Particle size analysis - Photon correlation spectroscopy
• ISO 14488 Particulate materials — Sampling and sample splitting for the determination of particulate properties — Amendment 1
• ISO 22412 Particle size analysis - Dynamic light scattering (DLS)

ASTM E2834-12 history

• 2022 ASTM E2834-12(2022) Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA)
• 2018 ASTM E2834-12(2018) Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA)
• 2012 ASTM E2834-12 Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA)