ISO 25101:2009 PDF

Scope: WARNING — Persons using this International Standard should be familiar with normal laboratory practice. This standard does not purport to address all of the safety problems, if any, associated with its use. It is the responsibility of the user to establish appropriate safety and health practices and to ensure compliance with any national regulatory conditions. IMPORTANT — It is absolutely essential that tests conducted in accordance with this International Standard be carried out by suitably qualified staff. This International Standard specifies a method for the determination of the linear isomers of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) in unfiltered samples of drinking water,ground water and surface water (fresh water and sea water) using high-performance liquid chromatographytandem mass spectrometry (HPLC-MS/MS). Other isomers may be reported separately as non-linear isomers and qualified as such. The analytes specified in Table 1 can be determined by this method. The method is applicable to a concentration range of 2,0 ng/l to 10 000 ng/l for PFOS and 10 ng/l to 10 000 ng/l for PFOA. Depending on the matrix, the method may also be applicable to higher concentrations ranging from 100 ng/l to 200 000 ng/l after suitable dilution of the sample or reduction in sample size. The user should be aware that particular problems could require the specification of additional conditions.

ISO 25101:2009 Referenced Document

ISO 3696:1987 Water for analytical laboratory use; Specification and test methods
ISO 5667-1 Water quality — Sampling — Part 1: Guidance on the design of sampling programmes and sampling techniques*， 2023-03-14 Update
ISO 8466-1 Water quality — Calibration and evaluation of analytical methods — Part 1: Linear calibration function*， 2021-11-17 Update

2009 ISO 25101:2009 Water quality - Determination of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) - Method for unfiltered samples using solid phase extraction and liquid chromatography/mass spectrometry