International Organization for Standardization (ISO)
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ISO/TS 22304:2008
Scope
This Technical Specification specifies the procedure for the determination of the tobacco specific nitrosamines
(TSNAs): N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N nitrosoanabasine (NAB) and
4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone (NNK) in ground leaf tobacco, manufactured tobacco and
tobacco products The determination is by means of gas chromatography.
ISO/TS 22304:2008 Referenced Document
ISO 1042 Laboratory glassware - One-mark volumetric flasks
ISO 3696 Water for analytical laboratory use; Specification and test methods
ISO/TS 22304:2008 history
2008ISO/TS 22304:2008 Tobacco - Determination of tobacco specific nitrosamines - Method using alkaline dichloromethane extraction