ASTM E993-05
Standard Test Method for Evaluation of Delayed Contact Hypersensitivity

Standard No.

ASTM E993-05

Release Date

2005

Published By

American Society for Testing and Materials (ASTM)

Status

Withdraw 2010-02

Latest

ASTM E993-05

Scope

This test method can be used to determine whether a test material will elicit skin sensitization or delayed contact
hypersensitivity in guinea pigs.^{3 ,4 ,5 ,6}

The results of this test method are a good indication of the potential for a given test material to produce delayed contact hypersensitivity in human beings under the appropriate conditions.

This test method can be used as a screening technique before conducting a similar test with human subjects.

1.1 This test method determines whether a test substance will elicit delayed-contact hypersensitivity in guinea pigs. The test method is applicable to individual chemical compounds, simple and complex mixtures, and also finished products.

1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

ASTM E993-05 history

• 2005 ASTM E993-05 Standard Test Method for Evaluation of Delayed Contact Hypersensitivity
• 2001 ASTM E993-01 Standard Test Method for Evaluation of Delayed Contact Hypersensitivity
• 1988 ASTM E993-88(1996)e1 Standard Test Method for Evaluation of Delayed Contact Hypersensitivity