ASTM D4626-95(2005)
Standard Practice for Calculation of Gas Chromatographic Response Factors

Standard No.

ASTM D4626-95(2005)

Release Date

1995

Published By

American Society for Testing and Materials (ASTM)

Status

Be replaced

Replace By

ASTM D4626-95(2010)

Latest

ASTM D4626-23

Scope

ASTM standard gas chromatographic methods for the analysis of petroleum products require calibration of the gas chromatographic system by preparation and analysis of specified reference mixtures. Frequently, minimal information is given in these methods on the practice of calculating calibration or response factors. Test Methods D 2268, D 2427, D 2804, D 2998, D 3329, D 3362, D 3465, D 3545, and D 3695 are examples. The present practice helps to fill this void by providing a detailed reference procedure for calculating response factors, as exemplified by analysis of a standard blend of C₆ to C₁₁ n-paraffins using n-C₁₂ as the diluent.

In practice, response factors are used to correct peak areas to a common base prior to final calculation of the sample composition. The response factors calculated in this practice are “multipliers” and prior to final calculation of the results the area obtained for each compound in the sample should be multiplied by the response factor determined for that compound.

It has been determined that values for response factors will vary with individual installations. This may be caused by variations in instrument design, columns, and experimental techniques. It is necessary that chromatographs be individually calibrated to obtain the most accurate data.

1.1 This practice covers a procedure for calculating gas chromatographic response factors. It is applicable to chromatographic data obtained from a gaseous mixture or from any mixture of compounds that is normally liquid at room temperature and pressure or solids, or both, that will form a solution with liquids. It is not intended to be applied to those compounds that react in the chromatograph or are not quantitatively eluted. Normal C6 through C11 paraffins have been chosen as model compounds for demonstration purposes.

1.2 The values stated in SI units are to be regarded as the standard. The values stated in inch-pound units are for information only.

1.3This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

ASTM D4626-95(2005) Referenced Document

• ASTM D2268 Standard Test Method for Analysis of High-Purity n-Heptane and Isooctane by Capillary Gas Chromatography*， 2017-10-01 Update
• ASTM D2427 Standard Test Method for Determination of C₂ through C₅ Hydrocarbons in Gasolines by Gas Chromatography
• ASTM D2804 Standard Test Method for Purity of Methyl Ethyl Ketone By Gas Chromatography*， 1998-04-19 Update
• ASTM D2998 Standard Test Method for Polyhydric Alcohols in Alkyd Resins*， 1996-01-01 Update
• ASTM D3329 Standard Test Method for Purity of Methyl Isobutyl Ketone by Gas Chromatography*， 1999-04-19 Update
• ASTM D3362 Standard Test Method for Purity of Acrylate Esters by Gas Chromatography
• ASTM D3465 Standard Guide for Purity of Monomeric Plasticizers by Gas Chromatography*， 2021-07-01 Update
• ASTM D3545 Standard Test Method for Alcohol Content and Purity of Acetate Esters by Gas Chromatography
• ASTM D3695 Standard Test Method for Volatile Alcohols in Water by Direct Aqueous-Injection Gas Chromatography*， 2021-11-01 Update
• ASTM D4307 Standard Practice for Preparation of Liquid Blends for Use as Analytical Standards*， 1999-04-19 Update
• ASTM E260 Standard Practice for Packed Column Gas Chromatography*， 2019-09-01 Update

ASTM D4626-95(2005) history

• 2023 ASTM D4626-23 Standard Practice for Calculation of Gas Chromatographic Response Factors
• 2019 ASTM D4626-95(2019) Standard Practice for Calculation of Gas Chromatographic Response Factors
• 1995 ASTM D4626-95(2015) Standard Practice for Calculation of Gas Chromatographic Response Factors
• 1995 ASTM D4626-95(2010) Standard Practice for Calculation of Gas Chromatographic Response Factors
• 1995 ASTM D4626-95(2005) Standard Practice for Calculation of Gas Chromatographic Response Factors
• 2000 ASTM D4626-95(2000) Standard Practice for Calculation of Gas Chromatographic Response Factors