ASTM E2864-18(2022)
Standard Test Method for Measurement of Airborne Metal Oxide Nanoparticle Surface Area Concentration in Inhalation Exposure Chambers using Krypton Gas Adsorption

Standard No.

ASTM E2864-18(2022)

Release Date

2022

Published By

American Society for Testing and Materials (ASTM)

Latest

ASTM E2864-18(2022)

Scope

1.1 This test method covers determination of surface area of airborne metal oxide nanoparticles in inhalation exposure chambers for inhalation toxicology studies. Surface area may be measured by gas adsorption methods using adsorbates such as nitrogen, krypton, and argon (Brunauer et al. (1),2 Anderson (2), Gregg and Sing (3)) or by ion attachment and mobilitybased methods (Ku and Maynard (4)). This test method is specific to the measurement of surface area by gas adsorption by krypton gas adsorption. The test method permits the use of any modern commercial krypton adsorption instruments but strictly defines the sample collection, outgassing, and analysis procedures for metal and metal oxide nanoparticles. Use of krypton is required due to the low overall surface area of particle-laden samples and the need to accurately measure the background surface area of the filter used for sample collection. Instrument-reported values of surface area based on the multipoint Brunauer, Emmett and Teller (BET) equation (Brunauer et al. (1), Anderson (2), Gregg and Sing (3)) are used to calculate surface area of airborne nanoparticles collected on a filter. 1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. State all numerical values in terms of SI units unless specific instrumentation software reports surface area using alternate units. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.4 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

ASTM E2864-18(2022) Referenced Document

• ASTM B922 Standard Test Method for Metal Powder Specific Surface Area by Physical Adsorption
• ASTM C1274 Standard Test Method for Advanced Ceramic Specific Surface Area by Physical Adsorption
• ASTM E2456 Standard Terminology Relating to Nanotechnology
• ASTM E691 Standard Practice for Conducting an Interlaboratory Study to Determine the Precision of a Test Method
• ISO 18757 Fine ceramics (advanced ceramics, advanced technical ceramics) - Determination of specific surface area of ceramic powders by gas adsorption using the BET method
• ISO 9277 Determination of the specific surface area of solids by gas adsorption — BET method

ASTM E2864-18(2022) history

• 2022 ASTM E2864-18(2022) Standard Test Method for Measurement of Airborne Metal Oxide Nanoparticle Surface Area Concentration in Inhalation Exposure Chambers using Krypton Gas Adsorption
• 2018 ASTM E2864-18 Standard Test Method for Measurement of Airborne Metal Oxide Nanoparticle Surface Area Concentration in Inhalation Exposure Chambers using Krypton Gas Adsorption
• 2013 ASTM E2864-13 Standard Test Method for Measurement of Airborne Metal and Metal Oxide Nanoparticle Surface Area Concentration in Inhalation Exposure Chambers using Krypton Gas Adsorption