T/HPCIA 006-2022
Cosmetics-Mild irritation-Zebrafish(Danio rerio) embryo assay (English Version)

Standard No.

T/HPCIA 006-2022

Language

Chinese, Available in English version

Release Date

2022

Published By

Group Standards of the People's Republic of China

Latest

T/HPCIA 006-2022

Scope

Compared with T/HPCIA 006-2021, the main technical changes in this standard, in addition to editorial modifications, are as follows: 　——Two terms and definitions of irritation and no observable effect concentration have been added; 　——The method principle of the experiment has been modified; 　———Modified the configuration method of embryo buffer water; 　——Modified the stock solution concentration of the positive control group; 　——Added experimental methods for pre-test; 　——Added experimental requirements for video recording; 　——Modified the requirements for result calculation ; 　——The test endpoints and evaluation indicators for result determination have been modified; 　——The blank control test and positive control for quality control have been modified; 　——The solvent control for quality control has been added; 　——Appendix D (informative appendix) cosmetics and Reference method for raw material pretreatment.

T/HPCIA 006-2022 history

• 2022 T/HPCIA 006-2022 Cosmetics-Mild irritation-Zebrafish(Danio rerio) embryo assay