API PUBL 27-32131-1980
ACUTE TOXICITY TESTS API #78-1 NEW COMPOSITE MOTOR OIL

Standard No.
API PUBL 27-32131-1980
Release Date
1980
Published By
API - American Petroleum Institute
Latest
API PUBL 27-32131-1980
Scope
ABSTRACT The test material@ API #78-1@New Composite Motor Oil@ was tested for potential acute toxicity@ using a battery of six tests: Primary Skin Irritation@ Primary Eye Irritation@ Skin Sensitization@ Acute Dermal Toxicity. Acute Oral Toxicity@ and Sub acute Dermal Toxicity. Materials@ methods@ and results of individual tests are presented in this report. The test material was found to produce slight primary skin irritation. Likewise@ when the test material was tested for acute dermal and sub acute dermal toxicity@ results showed skin irritation and dermal corrosion@ respectively. No signs of systemic toxicity@ however@ were observed for either test@ but histopathologic examination determined accompanying dermal toxicity.The oral median lethal dose@ i.e.@ oral LD50@ was greater than 25 m1/kg.The test material produced practically no primary eye irritation and was found to be non-sensitizing.

API PUBL 27-32131-1980 history




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