1.1 This guide deals with the measurement of mobility and zeta potential in systems containing biological material such as proteins, DNA, liposomes and other similar organic materials that possess particle sizes in the nanometer scale (<100 nm).
1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.
1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.
1.4 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.
ASTM E2865-12(2022) Referenced Document
ASTM E1470 Standard Test Method for Characterization of Proteins by Electrophoretic Mobility
ASTM E2456 Standard Terminology Relating to Nanotechnology
ISO 13099-1 Colloidal systems - Methods for zeta-potential determination - Part 1: Electroacoustic and electrokinetic phenomena
ISO 13099-2 Colloidal systems - Methods for zeta-potential determination - Part 2: Optical methods
ISO 13321 Particle size analysis - Photon correlation spectroscopy
ASTM E2865-12(2022) history
2022ASTM E2865-12(2022) Standard Guide for Measurement of Electrophoretic Mobility and Zeta Potential of Nanosized Biological Materials
2018ASTM E2865-12(2018) Standard Guide for Measurement of Electrophoretic Mobility and Zeta Potential of Nanosized Biological Materials
2012ASTM E2865-12 Standard Guide for Measurement of Electrophoretic Mobility and Zeta Potential of Nanosized Biological Materials