BS EN 17641:2022 Foodstuffs. Multimethod for the determination of aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 toxin, HT-2 toxin and zearalenone by LC-MS/MS
1 Scope
This document describes a method using isotopically labelled standards for the quantitative
determination of aflatoxins B 1 , B 2 , G 1 , G 2 and M 1 (AFB1, AFB2, AFG1, AFG2 and AFM1), ochratoxin A (OTA), deoxynivalenol (DON), zearalenone
(ZEN), T-2 and HT-2 toxins (T-2 and HT-2) and fumonisins B 1 and B 2 (FB1 and FB2) in foods by liquid chromatography (LC) coupled with tandem mass spectrometry
(MS/MS).
A specific immunoaffinity column (IAC) clean-up is needed for aflatoxins (AFs) and
OTA in food intended for infants and young children (e.g. infant cereals, milk-based
powders), in spices, in dried fruits and in nuts.
The method has been validated through an intercollaborative study on different commodity
groups: cereals and cereal-based products including food for infant and young children,
nuts, spices, dried fruits and milk powder. The measuring range of each mycotoxin
in these naturally contaminated and/or spiked food samples were:
—
AFB1:
0,085 7 µg/kg – 11,4 µg/kg;
—
AFB2:
...
BS EN 17641:2022 Referenced Document
EN ISO 3696 Water for Analytical Laboratory Use- Specification and Test Methods (ISO 3696 : 1987)
BS EN 17641:2022 history
2022BS EN 17641:2022 Foodstuffs. Multimethod for the determination of aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 toxin, HT-2 toxin and zearalenone by LC-MS/MS