ISO 23921:2020
Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS

Standard No.

ISO 23921:2020

Release Date

2020

Published By

International Organization for Standardization (ISO)

Latest

ISO 23921:2020

Scope

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

ISO 23921:2020 Referenced Document

• ISO 20778 Cigarettes - Routine analytical cigarette smoking machine - Definitions and standard conditions with an intense smoking regime
• ISO 20779 Cigarettes — Generation and collection of total particulate matter using a routine analytical smoking machine with an intense smoking regime AMENDMENT 1
• ISO 3402 Tobacco and tobacco products — Atmosphere for conditioning and testing*， 2023-01-30 Update
• ISO 8243 Cigarettes.Sampling

ISO 23921:2020 history

• 2020 ISO 23921:2020 Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS